Table 1 Baseline demographics and clinical characteristics of patients in the training and validation cohorts
Variables | Training cohort | Internal validation cohort | P value* | External validation cohort | P value# |
|---|---|---|---|---|---|
Age (years) (≤ 65/ > 65) | 378/126 | 158/58 | 0.602 | 101/41 | 0.352 |
Sex (Male/Female) | 420/84 | 179/37 | 0.879 | 117/25 | 0.792 |
Hepatitis (No/Yes) | 92/412 | 36/180 | 0.610 | 21/121 | 0.337 |
Tumor size (cm) (≤ 5/ > 5) | 270/234 | 113/103 | 0.757 | 70/72 | 0.367 |
Differentiation degree (High/medium/low) | 26/340/138 | 11/141/64 | 0.826 | 6/84/52 | 0.102 |
Microvascular invasion (Yes/No) | 268/236 | 106/110 | 0.313 | 69/73 | 0.334 |
Tumor number (Single/Multiple) | 455/49 | 193/23 | 0.704 | 122/20 | 0.137 |
Cirrhosis (No/Yes) | 206/298 | 100/116 | 0.177 | 55/87 | 0.646 |
PLT(109/L) (≤ 224/ > 224) | 424/80 | 183/33 | 0.841 | 116/27 | 0.374 |
PCT(%) (≤ 0.24/ > 0.24) | 412/92 | 182/34 | 0.416 | 118/24 | 0.711 |
PDW(fL) (≤ 12.5/ > 12.5) | 81/423 | 36/180 | 0.843 | 30/112 | 0.158 |
MPV(fL) (≤ 11.6/ > 11.6) | 249/255 | 107/109 | 0.947 | 82/60 | 0.079 |
P-LCR(%) (≤ 33/ > 33) | 152/352 | 60/156 | 0.521 | 50/92 | 0.251 |
PT(s) (≤ 10.2/ > 10.2) | 101/403 | 51/165 | 0.282 | 33/109 | 0.406 |
INR (≤ 1.01/ > 1.01) | 360/144 | 163/53 | 0.266 | 90/52 | 0.065 |
APTT(s) (≤ 26.5/ > 26.5) | 90/414 | 34/182 | 0.491 | 31/111 | 0.284 |
TT(s) (≤ 19.3/ > 19.3) | 397/107 | 169/47 | 0.874 | 121/21 | 0.089 |
FIB(g/L) (≤ 3.44/ > 3.44) | 390/114 | 167/49 | 0.984 | 100/42 | 0.087 |
AFP(ng/mL) (≤ 400/ > 400) | 328/176 | 133/83 | 0.369 | 96/46 | 0.576 |
CEA(ng/mL) (≤ 5/ > 5) | 400/104 | 182/34 | 0.126 | 119/23 | 0.311 |
CA199(U/mL) (≤ 37/ > 37) | 439/65 | 190/26 | 0.750 | 108/34 | 0.395 |