Fig. 3
From: Laparoscopic lavage in a purulent peritonitis model: impact on inflammatory proteins
Protein expression in abdominal fluid and serum of peritonitis-afflicted animals vs. sham-operated animals. Inflammatory proteins were analyzed by proximity extension immunoassay. The volcano plots display log2 fold change of the mean protein levels (peritonitis/sham) versus significance (Student’s t-test). Some significantly altered proteins (p < 0.05) are annotated. Eighty-four proteins were detected in the abdominal fluid of peritonitis-afflicted (n = 15) and sham (n = 3) animals (A), while 71 proteins were identified in serum from peritonitis-afflicted (n = 15) and sham (n = 5) animals (B). However, proteins under the detection level in sham animals but measurable in peritonitis-afflicted animals (CANT1, CCL20 in abdominal fluid; PLIN1, IL17F, IL1B, YES1, ITGB6 in serum) were included