Fig. 4

Detection of Th17, Treg, and Th17/Treg ratio in the blood from rats. A Proportion of Th17 and Treg cells analyzed by flow cytometry. Dynamic changes of Th17, Treg, and Th17/Treg ratio during treatment with the no appliance (B), fixed appliance (C), and invisible appliance (D). *P < 0.05, **P < 0.01 vs. control; #P < 0.05, ##P < 0.01 vs. model; &P < 0.05, &&P < 0.01 vs. scaling-0 day. E Comparison of Th17, Treg, and Th17/Treg in three treatment modalities. *P < 0.05, **P < 0.01 vs. no appliance; #P < 0.05, ##P < 0.01 vs. fixed appliance. n = 4 per group