Fig. 5

Effect of different treatment modalities on Th17-related transcription factor-RORγt. A Representative immunohistochemical staining images (positive staining for biomarkers (indicated by arrows) red to brown in color) and statistical analysis of RORγt. B mRNA expression level of RORγt detected by qRT-PCR. In the same treatment, *P < 0.05, **P < 0.01 vs. control; #P < 0.05, ##P < 0.01 vs. model; &P < 0.05, &&P < 0.01 vs. scaling-0 day. In the comparison of different treatment, *P < 0.05, **P < 0.01 vs. no appliance; #P < 0.05, ##P < 0.01 vs. fixed appliance. n = 4 per group