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  1. Severe traumatic brain injury (STBI) is one of the major causes of death and disability worldwide. The incidence and risk factors of enteral nutrition (EN)-associated diarrhea in older patients with STBI remai...

    Authors: Xiao-xiao Shi, Qiao-ling Zhang, Qian Li, Xiao-dan Lu, Li Fan, Jia-jiang Jiang, Xin-yi Tu, Qiu-si Hu and Li-zhu Wang
    Citation: European Journal of Medical Research 2025 30:253
  2. Vascular calcification (VC) is an important risk factor for cardiovascular events in patients undergoing maintenance hemodialysis (MHD); however, there is limited data on VC-related factors in patients beginni...

    Authors: Hao Xiong, Cuifang Sun, Jie Song, Yan Yu, Chang Wang and Fang Yuan
    Citation: European Journal of Medical Research 2025 30:252
  3. Three-dimensional printing (3DP) has emerged as a transformative technology in the field of central nervous system (CNS) tumours, offering innovative advancements in various aspects of diagnosis, treatment and...

    Authors: Wireko Andrew Awuah, Simran Karkhanis, Adam Ben-Jaafar, Jonathan Sing Huk Kong, Krishitha Meenu Mannan, Princess Afia Nkrumah-Boateng, Joecelyn Kirani Tan, Adeleke Oluwaseun Dorcas, Vallabh Shet, Muhammad Hamza Shah, Toufik Abdul-Rahman and Oday Atallah
    Citation: European Journal of Medical Research 2025 30:251
  4. Remimazolam recently became available as a sedative. The comparison of the respiratory suppression effects of remimazolam and propofol under deep sedation for colonoscopy was not thoroughly unclear, particular...

    Authors: Zhengjia Wang, Renshu Zhan, Liqun Mo, Jin Zhang, Jie Hu, Shoupeng Tan, Qiongzhen He, Ping Li, Wekong Sun, Xiaobin Wang, Jun Jiang, Li Liu, Yingying Zhang and Yiping Bai
    Citation: European Journal of Medical Research 2025 30:250
  5. Homologous recombination deficiency (HRD) affects breast cancer patients. Treatment guided by multigene testing may be particularly beneficial in HRD patients by using platinum-based drugs and poly ADP-ribose ...

    Authors: Jinsui Du, Lizhe Zhu, Chenglong Duan, Nan Ma, Yudong Zhou, Danni Li, Jianing Zhang, Jiaqi Zhang, Yalong Wang, Xi Liu, Yu Ren and Bin Wang
    Citation: European Journal of Medical Research 2025 30:249
  6. Inflammatory bowel disease (IBD) includes chronic inflammatory conditions, such as Crohn's disease and ulcerative colitis, characterized by impaired function of the intestinal mucosal epithelial barrier. In re...

    Authors: Jingying Zhou, Penghui Lu, Haolong He, Ruhan Zhang, Dican Yang, Qiong Liu, Qianyan Liu, Mi Liu and Guoshan Zhang
    Citation: European Journal of Medical Research 2025 30:248
  7. The high metastasis rate of lung cancer contributes to its low 5-year survival rate. Bone metastasis is a common complication in advanced lung cancer, adversely affecting postoperative recovery. This study inv...

    Authors: Guihua Hang, Xia Gu, Yuanyuan Gu, Ping Gan, Chunwang Hua and Aiming Chen
    Citation: European Journal of Medical Research 2025 30:247
  8. Male infertility contributes to 20–30% of infertility cases, yet traditional diagnostic and treatment methods face limitations in accuracy and consistency. Artificial intelligence (AI) promises to transform ma...

    Authors: Kowsar Qaderi, Foruzan Sharifipour, Mahsa Dabir, Roshanak Shams and Ali Behmanesh
    Citation: European Journal of Medical Research 2025 30:246
  9. Gestational diabetes mellitus (GDM) is the most common pregnancy complication, significantly affecting maternal and neonatal health. Polycystic ovary syndrome (PCOS) is a common endocrine disorder characterize...

    Authors: Jin Wang, Can Cui, Fei Hou, Zhiyan Wu, Yingying Peng and Hua Jin
    Citation: European Journal of Medical Research 2025 30:245
  10. The incidence of thyroid cancer (TC) is increasing in China, largely due to overdiagnosis from widespread screening and improved ultrasound technology. Identifying precise TC biomarkers is crucial for accurate...

    Authors: Gaofeng Hu, Wenyuan Niu, Jiaming Ge, Jie Xuan, Yanyang Liu, Mengjia Li, Huize Shen, Shang Ma, Yuanqiang Li and Qinglin Li
    Citation: European Journal of Medical Research 2025 30:244
  11. The ligation of the intersphincteric fistula tract (LIFT) procedure has garnered popularity with its success rates and purported sphincter–continence preservation. However, there remains a paucity in the liter...

    Authors: Ian Jse-Wei Tan, Bei En Siew, Jerrald Lau, Carol Pei Ling Yap, Stephanie Marie May Ee Soon and Ker-Kan Tan
    Citation: European Journal of Medical Research 2025 30:243
  12. The development of gene editing tools such as CRISPR-Cas9 and base editors (BE) is critical for genetic diseases and cancer. Lentivirus-like particles (LVLPs) grows into an auspicious platform for delivering m...

    Authors: Jinlin Jia, Yanzhe Hao, Lu Zhang, Xiaofang Cao, Lisha An, Hu Wang, Qi Ma, Xiaohua Jin and Xu Ma
    Citation: European Journal of Medical Research 2025 30:242
  13. To determine the optimal dexmedetomidine dose for hemodynamic stability and recovery quality in modified electroconvulsive therapy (MECT).

    Authors: Jun Shen, Min Zhou, Guangliang Zhu, Yu Zhang, Jinzhi Ma, Dekui Li, Lei Chen, Kejun Qi, Anjiang Wang, Yang Jiang, Zhiming Dai and Xiaoming Li
    Citation: European Journal of Medical Research 2025 30:241
  14. Authors: Thanh-Hai Tong, Xuan-Hai Do, Thanh-Thao Nguyen, Bich-Hanh Pham, Quang-Dung Le, Xuan-Hung Nguyen, Nhung Thi My Hoang, Thu-Huyen Nguyen, Nam Hoang Nguyen and Uyen Thi Trang Than
    Citation: European Journal of Medical Research 2025 30:240

    The original article was published in European Journal of Medical Research 2025 30:145

  15. Diabetic foot ulcer (DFU) is a severe diabetic complication. Transplantation of skin substitutes, stem cells, and platelet-rich plasma (PRP) treatments are promising tools to promote ulcer healing in diabetes....

    Authors: Forouzan Karam, Mahtab Sayadi, Saeedeh Dadi and Gholamreza Anani Sarab
    Citation: European Journal of Medical Research 2025 30:239
  16. This study aimed to explore the factors affecting pathologic complete response (pCR) and prognosis of locally advanced prostate cancer (LAPCa) or metastatic prostate cancer (mPCa) treated with neoadjuvant andr...

    Authors: Kaichen Zhou, Haosen Lu, Fukun Wei, Jie Wang, Zhen Song and Lijun Mao
    Citation: European Journal of Medical Research 2025 30:238
  17. Programmed cell death protein 1 (PD-1) is a key immune checkpoint involved in HIV-related immune escape, but its precise role and underlying mechanisms remain unclear. This study investigates the effects of PD...

    Authors: Xueru Lin, Bo Song, Lijun Cao, Lin Zhang, Siyu Liu, Xue Wang, Xiaohong Chen and Shuchen Li
    Citation: European Journal of Medical Research 2025 30:237
  18. The respiratory tract microbiome, a complex ecosystem of microorganisms colonizing the respiratory mucous layers and epithelial surfaces along with their associated microenvironment, plays a vital role in main...

    Authors: Yutao Ge, Guo Tang, Yawen Fu, Peng Deng and Rong Yao
    Citation: European Journal of Medical Research 2025 30:236
  19. Abnormal glycemic variability (GV), defined as acute fluctuations in blood glucose, is a prevalent phenomenon observed in critically ill patients and has been linked to unfavorable outcomes, including elevated...

    Authors: Yuyang Hou, Xinyi Guo and Jiasheng Yu
    Citation: European Journal of Medical Research 2025 30:235
  20. Alzheimer’s disease (AD) is the most prevalent neurodegenerative disorder, affecting tens of millions worldwide with projections indicating increasing prevalence in coming decades. Characterized by progressive...

    Authors: Xinlei Zhang, Lingling Zhu, Yuan Li, Hongna Yu, Tao Wang and Xiuli Chu
    Citation: European Journal of Medical Research 2025 30:233
  21. This study aims to investigate the improvement of stone fragmentation efficiency and safety in robotic-assisted retrograde intrarenal surgery (RIRS) that implements the respiratory motion synchronization using...

    Authors: Joonhwan Kim, Chinnakhet Ketsuwan, Kyu-Seob Song, Jae-chul Kim, Joonyeong Kim, Hyeji Park, Dong-Soo Kwon, Joo Yong Lee and Sung Yong Cho
    Citation: European Journal of Medical Research 2025 30:232
  22. Unilateral biportal endoscopic lumbar interbody fusion (UBE-LIF) has been successfully used to treat degenerative lumbar spinal diseases. Nevertheless, the duration of the UBE-LIF procedure notably exceeds tha...

    Authors: Guofang Fang, Jin Zhang, Hailun Zhu, Xunwei Lai, Jianchang Wu, Xiuwang Li, Zhouxu Hou, Fangxin Chen and Hongxun Sang
    Citation: European Journal of Medical Research 2025 30:231
  23. Voxel-based morphometry (VBM) reveals diverse alterations in gray matter volume in acute lymphoblastic leukemia (ALL) patients after chemotherapy. However, the reported results are inconsistent. Therefore, our...

    Authors: Xuelian Zong, Huiping Liu and Xiaoyun Zhao
    Citation: European Journal of Medical Research 2025 30:230
  24. The albumin–globulin ratio (AGR) is considered an important indicator reflecting an individual’s immune function and nutritional status, and it is closely associated with various health conditions. However, de...

    Authors: Yuan-Zhuo Du, Jia-Hao Liu, Fu-Chun Zheng, Qiang Zhou and Ju Guo
    Citation: European Journal of Medical Research 2025 30:229
  25. Numerous studies have investigated variables that predict mortality and complications following severe trauma. These studies, however, mainly focus on admission values or a single variable. The aim of this stu...

    Authors: Lea Gröbli, Yannik Kalbas, Franziska Kessler, Jakob Hax, Teuben Michel, Kai Sprengel, Roman Pfeifer, Martin Mächler, Hans-Christoph Pape, Sascha Halvachizadeh and Felix Karl-Ludwig Klingebiel
    Citation: European Journal of Medical Research 2025 30:228
  26. Addictive substance use disorder has a wide range of effects on the intestinal barrier, including damage to the biological, chemical, mechanical, and immune barriers. Damage to the intestinal barrier caused by...

    Authors: Yan Gao, Deshenyue Kong, Jia-xue Sun, Zhong-xu Ma, Guang-qing Wang, Xing-feng Ma, Liang Sun, Hua-you Luo, Yu Xu and Kun-hua Wang
    Citation: European Journal of Medical Research 2025 30:226
  27. With low early detection rates and high incidence and mortality, Gastrointestinal cancer (GIC) imposes a significant global health burden. Emerging evidence indicates that periodontitis may be a potential risk...

    Authors: Ting Luo, Juan Li, Ke Pu and Guodong Yang
    Citation: European Journal of Medical Research 2025 30:225
  28. Nasal mucosal epithelial hyperplasia can cause nasal hyperplastic diseases, more studies have confirmed that different subtypes of HPV infection play a significant role in nasal proliferative diseases, especia...

    Authors: Yi Zhang, Kaisai Tian, Liying Zheng, Gaohan Zhu, Runyu Zhao, Enhui Zhou, Xiaocheng Xue, Shuixian Huang, Xiaoping Chen, Baoji Hu and Wenhao Yao
    Citation: European Journal of Medical Research 2025 30:224
  29. Chronic airway inflammatory diseases, which primarily include chronic obstructive pulmonary disease (COPD), asthma, allergic rhinitis, and chronic sinusitis, continue to have a high global prevalence, highligh...

    Authors: Xing Yang, Wenqi Che, Lu Zhang, Huanping Zhang and Xiaoxue Chen
    Citation: European Journal of Medical Research 2025 30:223
  30. Maternal oxygen inhalation during labor has not been shown to provide significant benefits to newborns. However, its impact on fetal hemodynamics in late pregnancy remains uncertain.

    Authors: Xiu-Qin Wu, Xiao-Feng Yang, Lin Ye, Xiao-bin Zhang, Yong-Qiang Hong and Wei-Hsiu Chiu
    Citation: European Journal of Medical Research 2025 30:222
  31. Lung adenocarcinoma (LUAD) is a major contributor to global mortality. Grounded onto bioinformatics insights, this study probes the functions of dynein light chain LC8-type 1 (DYNLL1) in LUAD progression.

    Authors: Dapeng Li, An Wang, Xuan Wang, Mengkun Shi, Xiaofeng Chen, Yubao Lyu and Dayu Huang
    Citation: European Journal of Medical Research 2025 30:221
  32. The optimal red blood cell transfusion (RBCT) strategy for traumatic brain injury (TBI) patients remains a topic of debate. This systematic review and meta-analysis aimed to compare the outcomes of a liberal t...

    Authors: Jing Wang, Xiang-Hui Li, Jiang-Quan Yu and Rui-Qiang Zheng
    Citation: European Journal of Medical Research 2025 30:220
  33. Studies on the epidemiological characteristics, treatment strategies and prognosis of nasal and paranasal sinus cancer are still relatively limited.

    Authors: Zihan Chen, Zongwei Huang, Yuhui Pan, Youliang Weng, Zijie Wu, Jing Wang, Wenxi Wu, Xinyi Hong, Xin Chen and Sufang Qiu
    Citation: European Journal of Medical Research 2025 30:218
  34. Arteriovenous fistula stenosis is a common complication in hemodialysis patients, yet effective predictive tools are lacking. This study aims to develop an interpretable machine learning model for stenosis ris...

    Authors: Peng Shu, Ling Huang, Shanshan Huo, Jun Qiu, Haitao Bai, Xia Wang and Fang Xu
    Citation: European Journal of Medical Research 2025 30:217
  35. Aseptic prosthesis loosening caused by wear particles is a major complication in patients with osteoarthritis following total joint replacement. Despite advancements in treatment, the underlying mechanisms rem...

    Authors: Ping Chen, Hao-Hui Guo, Long Wu, Shuai Zhang, Qun-Hua Jin and Ke-Ning Sun
    Citation: European Journal of Medical Research 2025 30:216
  36. Severe community-acquired pneumonia (sCAP) is associated with higher morbidity and mortality. The use of glucocorticoids to improve the prognosis of severe community-acquired pneumonia remains a topic of contr...

    Authors: Xue Gu, Penglei Yang, Lina Yu, Jun Yuan, Ying Zhang, Zhou Yuan, Lianxin Chen, Xiaoli Zhang and Qihong Chen
    Citation: European Journal of Medical Research 2025 30:215
  37. Stomach adenocarcinoma (STAD) with microsatellite instability (MSI) is associated with a better prognosis compared to Non-MSI. This study aims to elucidate the differences in the tumor microenvironment (TME) o...

    Authors: Jianlong Zhou, Yucheng Zhang, Yongfeng Liu, Jiehui Li, Wenxing Zhang, Junjiang Wang, Xueqing Yao, Huolun Feng, Jiabin Zheng and Yong Li
    Citation: European Journal of Medical Research 2025 30:214
  38. Lymphoma presenting splenic invasion as the primary manifestation poses unique diagnostic and therapeutic challenges. This study aims to systematically analyze the clinical features, prognostic factors, and ou...

    Authors: Li Li, Mengqi Xiong, Lulu Wang, Lixia Zhu, Kui Zhao, Lijun Wang, Jingsong He and Xiujin Ye
    Citation: European Journal of Medical Research 2025 30:213
  39. Current evidence on the quality of sports activity in patients younger than 65 following dual mobility (DM) total hip arthroplasty (THA) is lacking, and whether this coupling allows better performance than sin...

    Authors: Riccardo D’Ambrosi, Filippo Maria Anghilieri, Federico Valli, Giovanni Palminteri, Guido Bandettini, Baldo Arcuri, Ilaria Mariani, Laura Mangiavini, Nicola Ursino and Filippo Migliorini
    Citation: European Journal of Medical Research 2025 30:212
  40. Given the role of thyroid hormones (THs) in metabolism, growth and development, their involvement in carcinogenesis and cancer progression in the context of bladder cancer (BC) warrants further investigation. ...

    Authors: Jia Wang, Lu Yang, Shigang Du, Yi Pan, Ling Zhao, Haihao Li, Zeping Zhou and Tingyu Ke
    Citation: European Journal of Medical Research 2025 30:211
  41. The objective of this study was to elucidate the relationship between sperm DNA damage and sperm parameters in male infertility patients and to assess the changes in sperm DNA fragmentation index before and af...

    Authors: Kangsheng Liu, Yajunchen, Xiangdong Wang, Mengjie Zhao, Shimin Wu and Ruifang An
    Citation: European Journal of Medical Research 2025 30:210
  42. This study investigated the effect of a comprehensive pulmonary rehabilitation (CPR) program on stroke-associated pneumonia (SAP) in patients with moderate-to-severe acute ischemic stroke (AIS) after thromboly...

    Authors: QingSha Zhang, HongKun Liu, Jie Sun and HongGe Shi
    Citation: European Journal of Medical Research 2025 30:208
  43. Assisted reproductive technology (ART) has been widely used to treat infertility for more than four decades, but its efficacy is still lower than expected. Therefore, further exploration of the factors that af...

    Authors: Sui-Bing Miao, Geng Tian, Zhen-Chuan Zhao, Xiao-Wei Wang, Jian Zhao and Cai-Ping Geng
    Citation: European Journal of Medical Research 2025 30:207

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